Quantitative data were compared by the Mann-Withney U test. Anti-Xa activity was determined by chromogenic assay and the inhibition of endogenous thrombin potential (ETP) by thrombinography. Enox and Enox/Eth were diluted in whole blood at a final Enox concentration of 0.5, 1 (N = 6 samples), 1.5 (N = 4) and 2 (N = 6) IU/mL. This study assessed the anticoagulant properties of Enox/Eth. Enoxaparin 400 UI/mL–40 % ethanol (Enox/Eth) has antibiofilm properties and therefore has promise as an alternative lock solution. In contrast to UFH, enoxaparin (Enox) can be combined with 40 % ethanol without precipitation. Ethanol at a content ≥40 %v/v eradicates experimental biofilm but has no anticoagulant properties. Unfractionated heparin (UFH) is the most widely used interdialytic lock solution but has no anti-infectious properties.
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